The Specificity of Cerebroside Sulfatase Activator

  • Gisèle Dubois
  • Martial Masson
  • Carole Rosenthal
Part of the NATO ASI Series book series (NSSA, volume 116)


The unability for the lysosomal lipid hydrolases to act on their natural substrate alone, has been reported a long time ago (1). They showed the necessity to add a “detergent-like” natural protein called activator protein which allows the hydrolysis of the sulfatides by cerebroside sulfatase.


Activator Protein Sodium Cholate Fatty Acid Moiety Ceramide Moiety Detergent Enzyme 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Gisèle Dubois
    • 1
  • Martial Masson
    • 1
  • Carole Rosenthal
    • 1
  1. 1.Laboratoire de NeurochimieINSERM U 134 Hôpital de la SalpêtrièreParis cedex 13France

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