Immunological Studies on Acidic Sphingomyelinase
Intrinsic properties of acidic sphingomyelinase cause major difficulties in attempts to produce a satisfactory antibody. The only two published papers do not carry conviction: the monoclonal antibody described by Freeman et al. (1983) was not demonstrated to precipitate sphingomyelinase activity while monospecificity of the polyclonal antibody prepared from a urine source by Weitz et al. (1985) is questionable.
KeywordsPhosphoryl Choline Final Preparation Pure Preparation Sphingomyelinase Activity Goat Antirabbit Antibody
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