Monoacylglycerol Acyltransferase: Stereospecificity and Evidence that the Hepatic and Intestinal Activities are Tissue-Specific Isoenzymes

  • Rosalind A. Coleman
  • Elaine B. Haynes
  • James P. Walsh
  • David S. Millington
  • David A. Maltby
Part of the NATO ASI Series book series (NSSA, volume 116)


The transition from fetal to postnatal life is marked by dramatic changes in hepatic carbohydrate and lipid metabolism, as the supply of maternally-provided glucose ceases and the newborn becomes dependent on milk triacylglycerol for its energy and biosynthetic requirements. In perinatal rat liver, the enzyme activities involved in glycogen synthesis, gluconeogenesis, fatty acid oxidation and ketone body formation, rise whereas enzyme activities required for the synthesis of fatty acids decline (1–6).


Intestinal Mucosa Fatty Acid Oxidation Postnatal Development Acyl Transferase Diacylglycerol Kinase 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Rosalind A. Coleman
    • 1
  • Elaine B. Haynes
    • 1
  • James P. Walsh
    • 1
  • David S. Millington
    • 1
  • David A. Maltby
    • 1
  1. 1.Departments of Pediatrics and BiochemistryDuke University Medical CenterDurhamUSA

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