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Acetyltransferases and Transacylases Relative Rates in 1-Alkyl- or 1-Acyl-Phosphatidylcholine Synthesis by Rat Platelet Homogenates

  • Monique Cornic
  • Michelyne Breton
  • Odile Colard
Part of the NATO ASI Series book series (NSSA, volume 116)

Abstract

A number of enzymatic pathways leading to phospholipid synthesis by lysoderivative acylation have been identified in some cells and particularly in platelets. As known for a long time acylation depends on acyl-CoA synthesis in the presence of ATP and CoA with a high specificity of the acyl-CoA : acyltransferase for polyunsaturated fatty acids (1). Platelets also contain two different acyl-CoA synthetase : an arachidonyl-CoA specific synthetase and an acyl-CoA having no specificity for the acyl group (2).

Keywords

Phospholipid Synthesis Platelet Suspension Thin Layer Chromato Pancreatic Phospholipase Thrombin Stimulation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviation

GPC

glycero-phosphoryl-choline

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Monique Cornic
    • 1
  • Michelyne Breton
    • 1
  • Odile Colard
    • 1
  1. 1.Service de BiochimieC.H.U. Saint-AntoineParis Cedex 12France

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