Acetyltransferases and Transacylases Relative Rates in 1-Alkyl- or 1-Acyl-Phosphatidylcholine Synthesis by Rat Platelet Homogenates

  • Monique Cornic
  • Michelyne Breton
  • Odile Colard
Part of the NATO ASI Series book series (NSSA, volume 116)


A number of enzymatic pathways leading to phospholipid synthesis by lysoderivative acylation have been identified in some cells and particularly in platelets. As known for a long time acylation depends on acyl-CoA synthesis in the presence of ATP and CoA with a high specificity of the acyl-CoA : acyltransferase for polyunsaturated fatty acids (1). Platelets also contain two different acyl-CoA synthetase : an arachidonyl-CoA specific synthetase and an acyl-CoA having no specificity for the acyl group (2).


Phospholipid Synthesis Platelet Suspension Thin Layer Chromato Pancreatic Phospholipase Thrombin Stimulation 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Monique Cornic
    • 1
  • Michelyne Breton
    • 1
  • Odile Colard
    • 1
  1. 1.Service de BiochimieC.H.U. Saint-AntoineParis Cedex 12France

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