Phosphate Transport Through Placenta Brush Border Membrane

  • Michèle G. Brunette
  • Sylvie Letendre
  • Serge Allard
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 208)


During the whole gestation, and particularly the third trimester, large quantities of inorganic phosphate (PO4) move from the mother to the foetus against a concentration gradient. Since intracellular PO4 concentration is believed to be higher than in plasma, it is probable that PO4 is actively transported through the brush border membrane (BBM) facing the maternal side of placenta. Moreover in total placenta perfusion experiments, Stulc et al. (1982–1984) reported that PO4 transport is dependent on Na concentration in the perfusate, suggesting that in placenta, as in the intestine and the kidney, PO4 is co-transported with Na.


Brush Border Membrane Phosphate Transport Brush Border Membrane Vesicle Renal Brush Border Membrane Renal Brush Border Membrane Vesicle 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Michèle G. Brunette
    • 1
  • Sylvie Letendre
    • 1
  • Serge Allard
    • 1
  1. 1.Department of PediatricsUniversity of Montreal Maisonneuve HospitalMontrealCanada

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