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Mechanisms of NAD Action in Regulation of Renal Brush Border Membrane Transport of Phosphate

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Phosphate and Mineral Homeostasis

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 208))

Abstract

Many different hormonal and non-hormonal stimuli change the rate of phosphate (Pi) transport across the renal brush border membrane (BBM) (1,2, 3) which probably reflects the central role of proximal tubular reabsorption in renal handling of Pi. Based on considerations of (a) the time required for the effects of these stimuli to induce a response, and (b) whether the response is dependent upon intact de novo protein synthesis, it appears that the various stimuli may act intracellularly through at least two general mechanisms (2).

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Author information

Authors and Affiliations

  1. Department of Physiology and Biophysics, Indiana University Medical School, Indianapolis, IN, USA

    Stephen A. Kempson & Thomas P. Dousa

  2. Nephrology Research Unit, Mayo Clinic and Mayo Medical School, Rochester, MN, USA

    Stephen A. Kempson & Thomas P. Dousa

Authors
  1. Stephen A. Kempson
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  2. Thomas P. Dousa
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Editor information

Editors and Affiliations

  1. University of Southern California, Los Angeles, California, USA

    Shaul G. Massry

  2. University of Aix-Marseille, Marseille, France

    Michel Olmer

  3. University of Heidelberg, Heidelberg, Federal Republic of Germany

    Eberhard Ritz

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© 1986 Plenum Press, New York

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Kempson, S.A., Dousa, T.P. (1986). Mechanisms of NAD Action in Regulation of Renal Brush Border Membrane Transport of Phosphate. In: Massry, S.G., Olmer, M., Ritz, E. (eds) Phosphate and Mineral Homeostasis. Advances in Experimental Medicine and Biology, vol 208. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5206-8_5

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  • DOI: https://doi.org/10.1007/978-1-4684-5206-8_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5208-2

  • Online ISBN: 978-1-4684-5206-8

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