Changes in Serum Calcium and Phosphorus Induced by Chronic Renal Failure in the Absence of Parathyroid Hormone

  • Mariano Rodriguez
  • Victor Lorenzo
  • Arnold J. Felsenfeld
  • Francisco Llach
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 208)


In the animal models of renal failure, despite the absence of parathyroid hormone (PTH), suppressed tubular reabsorption of phosphate is observed. Thus, processes independent of PTH result in enhancement of phosphate excretion even in chronic renal failure, as has been demonstrated in uremic parathyroidectomized dogs by Swenson et al (1).


Parathyroid Hormone Chronic Renal Failure Serum Calcium Fractional Excretion Tubular Reabsorption 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Mariano Rodriguez
    • 1
  • Victor Lorenzo
    • 1
  • Arnold J. Felsenfeld
    • 1
  • Francisco Llach
    • 1
  1. 1.Nephrology Section, Department of MedicineUniversity of Oklahoma Health Sciences Center and VA Medical CenterOklahoma CityUSA

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