Serum Bone Gla-Protein Compared to Bone Histomorphometry in Hemodialyzed Patients

  • Sam A. Charhon
  • Pierre D. Delmas
  • Luc Malaval
  • Pascale M. Chavassieux
  • Marie Claire Chapuy
  • Pierre J. Meunier
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 208)


Bone gla-protein (BGP), also called osteocalcin1,2, is the most abundant non-collagenous bone protein. BGP is synthesized by the osteoblasts, is concentrated in the bone matrix and also found circulating in the blood. The measurement of BGP in serum by radioimmunoassay3 has proved to be a useful tool for assessing bone turnover in a variety of metabolic or endocrine bone diseascs4–6 and more specifically bone formation in osteoporosis7.


Serum Alkaline Phosphatase Bone Formation Rate Serum Biochemical Parameter Serum iPTH Serum Alkaline Phosphatase Level 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Sam A. Charhon
    • 1
  • Pierre D. Delmas
    • 1
  • Luc Malaval
    • 1
  • Pascale M. Chavassieux
    • 1
  • Marie Claire Chapuy
    • 1
  • Pierre J. Meunier
    • 1
  1. 1.INSERM U 234Faculté A. CarrelLyonFrance

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