Calcium Absorption in the Rat Colon Measured in Vivo

  • Patrick Ammann
  • René Rizzoli
  • Herbert Fleisch
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 208)


Calcium absorption in the large intestine was studied under physiological conditions in the rat. When 45Ca was administered directly into the caecum, the isotope was significantly absorbed. This absorption was modulated by dietary Ca and Pi as well as by the 1,25 (OH)2 D3 status. On the other hand, calcium coming from the food, either as 45Ca or as 45Ca, was not absorbed to a significant amount. When the absorption of 45Ca from the caecal content was assessed in duodenal loops, less 45Ca was absorbed when the isotope was administered orally than when it was added to the caecal content. Thus, the fact that oral Ca is not absorbed in the colon despite the efficient Ca transport system of this part of the intestine may be due to the transformation in the digestive tract of Ca from an absorbable into a non-absorbable form.


Calcium Absorption Large Intestine Dietary Calcium Calcium Transport Bovine Growth Hormone 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Patrick Ammann
    • 1
  • René Rizzoli
    • 1
  • Herbert Fleisch
    • 1
  1. 1.Department of PathophysiologyUniversity of BernBernSwitzerland

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