Renal Proximal Tubular Brush-Border Membrane Transport of Phosphate with Acute Acidosis
Recent studies from our laboratory (1) and that of other investigators (2) have shown that metabolic acidosis of several days duration is associated with suppression of phosphate transport by isolated brush-border membrane vesicles (BBMV) of the proximal tubule. The suppression is specific for the Pi transporter, since other Na-dependent transport processes are not altered.
KeywordsMetabolic Acidosis Phosphate Transport Respiratory Acidosis Renal Brush Border Membrane Renal Brush Border Membrane Vesicle
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