Possible Role of Calcium in Parathyroid Hormone Action on Phosphate Transport in Rabbit Renal Proximal Tubules

  • Norimoto Yanagawa
  • Ok D. Jo
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 208)


In the renal proximal tubule, parathyroid hormone (PTH) stimulates gluconeogenesis (GNG) and suppresses fluid and phosphate reabsorption. Since PTH stimulates cAMP formation in this nephron segment, and the administration of cAMP reproduces hormonal actions, it is generally accepted that PTH exerts its biological effects through cAMP as the intracellular messenger.


Parathyroid Hormone Brush Border Membrane Phosphate Transport Phosphate Uptake Renal Proximal Tubule 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Norimoto Yanagawa
    • 1
    • 2
  • Ok D. Jo
    • 1
    • 2
  1. 1.Nephrology Division, Medical and Research ServicesVeterans Administration Medical CenterSepulvedaUSA
  2. 2.Department of MedicineUCLA School of MedicineLos AngelesUSA

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