Acetylcholine Turnover in Mouse Brain: Influence of Cholinesterase Inhibitors

  • B. Karlén
  • G. Lundgren
  • J. Lundin
  • B. Holmstedt
Part of the Advances in Behavioral Biology book series (ABBI, volume 30)


Evidence has been presented to indicate that in neurons the concentrations of neurotransmitters are maintained at constant levels although the rates of transmitter metabolism are changing (10, 13). However, in cholinergic neurons there is evidence to show that concentrations of acetylcholine (ACh) are accompanied by changes in the rate of metabolism of this transmitter (11).


Turnover Rate Mass Fragmentography Propionyl Chloride Fractional Rate Constant Focus Microwave Irradiation 


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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • B. Karlén
    • 2
  • G. Lundgren
    • 1
  • J. Lundin
    • 1
  • B. Holmstedt
    • 1
  1. 1.Department of Toxicology The Swedish Medical Research CouncilKarolinska InstitutetStockholmSweden
  2. 2.Research DepartmentKabiVitrum ABStockholmSweden

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