Long Term Potentiation of Cholinergic Transmission in the Sympathetic Ganglion

  • C. A. Briggs
  • D. A. McAfee
Part of the Advances in Behavioral Biology book series (ABBI, volume 30)


Long term potentiation (LTP), like the better known posttetanic potentiation (PTP), is a use-dependent increase in synaptic efficacy. Both potentiations are induced after repetitive synaptic stimulation for a few seconds. But while posttetanic potentiation decays away in a few minutes after the tetanic stimulation, long term potentiation continues for hours or even longer (7, 14, 27). The striking disparity between the endurance of long term potentiation and the brevity of its induction suggests a metabolic modulation of synaptic transmission.


Long Term Potentiation Sympathetic Ganglion Compound Action Potential Tetanic Stimulation Synaptic Efficacy 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • C. A. Briggs
    • 1
  • D. A. McAfee
    • 1
  1. 1.Division of NeurosciencesBeckman Research Institute City of HopeDuarteUSA

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