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Pharmacological Characterization of Axonally Transported [125I]-α-Bungarotoxin Binding Sites in Rat Sciatic Nerve

  • E. Aizenman
  • W. R. Millington
  • M. A. Zarbin
  • G. G. Bierkamper
  • M. J. Kuhar
Part of the Advances in Behavioral Biology book series (ABBI, volume 30)

Abstract

Cholinergic receptors are known to occur at the postsynaptic membrane of the mammalian neuromuscular junction. It has been proposed that cholinergic drugs may also act at the motor nerve terminal (rev. 5, 20, 27, 28). However, there is as yet no conclusive evidence that demonstrates that these drug effects occur via an acetylcholine receptor on the presynaptic membrane (4, 6, 14, 17, 30).

Keywords

Cholinergic Receptor Optic Lobe Presynaptic Membrane Motor Nerve Terminal Cholinergic Drug 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Aizenman, E., Millington, W., Zarbin, M., Bierkamper, G. and Kuhar, M. (1983): Fed. Proc. 42: 1147.Google Scholar
  2. 2.
    Barnard, E. and Dolly, J. (1982): T.I.N.S. 5: 325–327.Google Scholar
  3. 3.
    Barstard, J. (1962): Experientia 18: 579–580.CrossRefGoogle Scholar
  4. 4.
    Blaber, L. (1970): J. Pharm. Exp. Ther. 175: 664–672.Google Scholar
  5. 5.
    Bowman, W. (1980): Anaesth. Analg. 59: 935–943.CrossRefGoogle Scholar
  6. 6.
    Bowman, W. and Webb, S. (1976): Clin. Exp. Pharm. Phys. 3: 545–555.CrossRefGoogle Scholar
  7. 7.
    Chang, C. and Lee, C. (1963): Arch. Int. Pharmacodyn. 144: 241–257.Google Scholar
  8. 8.
    Eccles, J., Katz, B. and Kuffler, S.W. (1942): J. Neurophysiol. 5: 211–230.Google Scholar
  9. 9.
    Feng, T. and Li, T. (1941): Chin. J. Physiol. 16: 37–50.Google Scholar
  10. 10.
    Fertuck, H. and Salpeter, M. (1976): J. Cell Biol. 69: 144–158.CrossRefGoogle Scholar
  11. 11.
    Freedman, S. and Lentz, T. (1980): J. Comp. Neurol. 193: 179185.Google Scholar
  12. 12.
    Fumagali, L., de Renzis, G. and Miani, N. (1976): J. Neurochem. 27: 47–52.CrossRefGoogle Scholar
  13. 13.
    Glavinovik, M. (1979): J. Physiol. 290: 499–506.Google Scholar
  14. 14.
    Hohlfeld, R., Sterz, R. and Peper, K. (1981): Pflugers Arch. 391: 213–218.CrossRefGoogle Scholar
  15. 15.
    Hubbard, J., Schmidt, R. and Yokota, T. (1965): J. Physiol. 181: 810–829.Google Scholar
  16. 16.
    Jones, S. and Salpeter, M. (1983): J. Neurosci. 3: 326–331.Google Scholar
  17. 17.
    Katz, B. (1962): Proc. Roy. Soc. Lond. 155: 455–477.CrossRefGoogle Scholar
  18. 18.
    Lentz, T. Mazurkiewicz, J. and Rosenthal, J. (1977): Brain Res. 132: 423–442.CrossRefGoogle Scholar
  19. 19.
    Masland, R. and Wigton,R. (1940): J. Neurophysiol. 3: 269–275.Google Scholar
  20. 20.
    Miyamoto, M.D. (1978): Pharm. Rev. 29: 221–247.Google Scholar
  21. 21.
    Morley, B. and Kemp, G. (1981): Brain Res. Rev. 3: 81–104.CrossRefGoogle Scholar
  22. 22.
    Ninkovic, M. and Hunt, S. (1983): Brain Res. 272: 57–69.CrossRefGoogle Scholar
  23. 23.
    Oswald, R. and Freeman, J. (1981): Neurosci. 6: 1–4.CrossRefGoogle Scholar
  24. 24.
    Polz-Tejera, G., Hunt, S. and Schmidt, J. (1980): Brain Res. 195: 223–230.CrossRefGoogle Scholar
  25. 25.
    Randic, M. and Straughan, D. (1964): J. Physiol. 173: 130–148.Google Scholar
  26. 26.
    Rang, H. (1981): Postgr. Med. J. 57 (Suppl. 1): 89–97.MathSciNetGoogle Scholar
  27. 27.
    Riker, W. and Okamoto, M. (1969): Ann. Rev. Pharmacol. 9: 173–208.CrossRefGoogle Scholar
  28. 28.
    Standaert, F. (1982): Br. J. Anaesth. 54: 131–144.CrossRefGoogle Scholar
  29. 29.
    Wamsley, J., Zarbin, M. and Kuhar, M. (1981): Brain Res. 217: 155–161.CrossRefGoogle Scholar
  30. 30.
    Webb, S. and Bowman, W. (1974): Clin. Exp. Pharm. Phys. 1: 123–134.CrossRefGoogle Scholar
  31. 31.
    Werner, G. (1960): J. Neurophysiol. 23: 171–187.Google Scholar
  32. 32.
    Young, W. and Kuhar, M. (1979): Brain Res. 179: 255–270.CrossRefGoogle Scholar
  33. 33.
    Young, W., Wamsley, J., Zarbin, M. and Kuhar, M. (1980): Science 210: 76–78.CrossRefGoogle Scholar
  34. 34.
    Zarbin, M., Wamsley, J. and Kuhar, M. (1982): J. Neurosci 2: 934–941.Google Scholar

Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • E. Aizenman
    • 1
  • W. R. Millington
    • 3
  • M. A. Zarbin
    • 2
  • G. G. Bierkamper
    • 4
  • M. J. Kuhar
    • 2
  1. 1.Department of Environmental Health SciencesThe Johns Hopkins UniversityBaltimoreUSA
  2. 2.Department of NeuroscienceThe Johns Hopkins UniversityBaltimoreUSA
  3. 3.Experimental Therapeutics BranchNIH-NINCDSBethesdaUSA
  4. 4.School of Medicine, Department of PharmacologyUniversity of Nevada School of MedicineRenoUSA

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