Studies on the Synaptic Function in Muscle after Nerve Crush in Normal and Diabetic Rats

  • R. Siliprandi
  • S. Consolo
  • F. Di Gregorio
  • H. Ladinsky
  • C. Scozzesi
  • R. Zanoni
  • A. Gorio
Part of the Advances in Behavioral Biology book series (ABBI, volume 30)

Abstract

Spontaneous diabetes can develop a neuropathy that affects function and morphology of the peripheral nerves both in men and in animals (7, 14, 16, 22). Diabetes can also be induced by a single injection of Alloxan or Streptozotocin (15), drugs that exert a toxic effect on the beta-cells of the Langerhans islets. In rats treated with either. Alloxan or Streptozotocin a decrease in nerve conduction velocity is evident within a few weeks after intoxication (3, 20).

Keywords

Extensor Digitorum Longus Extensor Digitorum Longus Muscle Sciatic Nerve Crush Radioenzymatic Assay Synaptic Maturation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • R. Siliprandi
    • 1
  • S. Consolo
    • 2
  • F. Di Gregorio
    • 1
  • H. Ladinsky
    • 2
  • C. Scozzesi
    • 2
  • R. Zanoni
    • 1
  • A. Gorio
    • 1
  1. 1.Department of CytopharmacologyFidia Research LaboratoriesAbano TermeItaly
  2. 2.Cholinergic NeuropharmacologyMario Negri Institute for Pharmacological ResearchMilanItaly

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