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Washout of Small Boluses of Oxygenated or Deoxygenated Fluorocarbons from Canine Hindlimb

  • N. S. Faithfull
  • C. E. King
  • S. M. Cain
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 200)

Abstract

Hyperoxia decreased capillary perfusion in rabbit tenuissimus muscle (Lindbom and Arfors, 1984) and in hamster cheek pouch (Duling, 1972). These changes would have increased inhomogeneity of red cell transit times. We wished to demonstrate a similar effect in canine hindlimb vasculature by washing in a hyperoxic bolus of a fluorocarbon emulsion (FC-43). The greater solubility of O2 in FC-43 was expected to have a greater effect that either saline or dextran on the more distal portions of the precapillary control vessels because of the lesser fall in PO2 in transit.

Keywords

Suxamethonium Chloride Limb Blood Flow Hamster Cheek Pouch Washout Curve Small Bolus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • N. S. Faithfull
    • 1
    • 2
  • C. E. King
    • 1
    • 2
  • S. M. Cain
    • 1
    • 2
  1. 1.Department of Experimental AnaesthesiaErasmus UniversityRotterdamThe Netherlands
  2. 2.Department of Physiology and BiophysicsUniversity of Alabama at BirminghamUSA

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