In Vivo Effects of PAF-Acether and Arterial Thrombosis
Platelet-activating factor (PAF) was first described in 1972 (1), after a soluble intermediate was demonstrated originating from rabbit leukocytes and thought to be responsible for the liberation of histamine from rabbit platelets (2). Structural analysis indicated that PAF was a 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (3); as such it was termed PAF-acether.
KeywordsPlatelet Activate Factor Arterial Thrombosis Rabbit Platelet Platelet Thrombus Arthus Reaction
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