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The Influence of Moderate Hypothermia on Cerebral Cortex Tissue Oxygen Tension

  • Hermann Metzger
  • Helmut Brüggemann
  • Anke Plewnia
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 200)

Summary

The validity of mechanisms balancing oxygen transport and consumption in hypothermia are difficult to analyse because almost any parameter of the transport system is temperature dependent. Two types of experiments have been performed in the rat cerebral cortex to elucidate this problem:
  1. I)

    PO2 microelectrode study: 32–37°C bodytemperature, spontaneous respiration. Measurements within the upper tissue layer of 200–500 um thickness (N=15).

     
  2. II)

    PO2 surface electrode study: 26–37°C body temperature, artificial respiration. Investigation of the arachnoidal and pial area (N=46).

     

Keywords

Cerebral Blood Flow Mean Arterial Pressure Spontaneous Respiration Local Cerebral Blood Flow Heat Exchanger System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Hermann Metzger
    • 1
  • Helmut Brüggemann
    • 1
  • Anke Plewnia
    • 1
  1. 1.Dept. PhysiologyMedizinische Hochschule HannoverHannover 61Federal Republic of Germany

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