A Mutagen is a Mutagen, Not Necessarily a Carcinogen
A largely unspoken but underlying assumption that has been made by authors throughout these proceedings is that processes involved in antimutagenesis are related to anticarcinogenesis, a corollary of the somatic mutation theory of carcinogenesis. It is generally known that most carcinogens are mutagens, but certainly not all chemicals that are mutagenic in short-term in vitro mutagenicity tests are carcinogens. Reasons that contribute to this lack of concordance are discussed later.
KeywordsUnderlying Assumption Mutagenicity Test Toxicology Evaluation Section Department Mutation Theory
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