A Mutagen is a Mutagen, Not Necessarily a Carcinogen

  • Earle R. Nestmann
Part of the Basic Life Sciences book series (BLSC, volume 39)


A largely unspoken but underlying assumption that has been made by authors throughout these proceedings is that processes involved in antimutagenesis are related to anticarcinogenesis, a corollary of the somatic mutation theory of carcinogenesis. It is generally known that most carcinogens are mutagens, but certainly not all chemicals that are mutagenic in short-term in vitro mutagenicity tests are carcinogens. Reasons that contribute to this lack of concordance are discussed later.


Underlying Assumption Mutagenicity Test Toxicology Evaluation Section Department Mutation Theory 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Earle R. Nestmann
    • 1
  1. 1.Department of National Health and WelfareMutagenesis SectionOttawaCanada

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