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Antimutagenesis and Anticarcinogenesis Mechanisms pp 343–348Cite as

Multiple Inducible Cytochromes P-450 in Yeast

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Part of the book series: Basic Life Sciences ((BLSC,volume 39))

Abstract

A form of cytochrome P-450 is produced in Saccharomyces cerevisiae during the logarithmic growth phase (14). This form is inhibited by metyrapone, tetrahydrofurane, and carbon oxide which are inhibitors of ethanolinducible cytochromes P-450 of mammals. Addition of Na-phenobarbital to the 0.5% glucose liquid medium induced a form of cytochrome P-450 inhibited only by metyrapone. Thus, yeast possess multiple forms of cytochrome P-450 that are individually inducible.

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Author information

Authors and Affiliations

  1. Istituto di Mutagenesi e Differenziamento CNR, 56100, Vie Svezie 10, Pisa, Italy

    G. Bronzetti & R. Del Carratore

Authors
  1. G. Bronzetti
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  2. R. Del Carratore
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Editor information

Editors and Affiliations

  1. University of Kansas, Lawrence, Kansas, USA

    Delbert M. Shankel

  2. Johns Hopkins University, Baltimore, Maryland, USA

    Philip E. Hartman

  3. National Institute of Genetics, Mishima, Japan

    Tsuneo Kada

  4. Council for Research Planning in Biological Sciences, Inc., Washington, D.C., USA

    Alexander Hollaender , Claire M. Wilson  & Gregory Kuny ,  & 

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© 1986 Plenum Press, New York

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Bronzetti, G., Del Carratore, R. (1986). Multiple Inducible Cytochromes P-450 in Yeast. In: Shankel, D.M., Hartman, P.E., Kada, T., Hollaender, A., Wilson, C.M., Kuny, G. (eds) Antimutagenesis and Anticarcinogenesis Mechanisms. Basic Life Sciences, vol 39. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5182-5_29

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  • DOI: https://doi.org/10.1007/978-1-4684-5182-5_29

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5184-9

  • Online ISBN: 978-1-4684-5182-5

  • eBook Packages: Springer Book Archive

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