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Multiple Inducible Cytochromes P-450 in Yeast

  • G. Bronzetti
  • R. Del Carratore
Part of the Basic Life Sciences book series (BLSC, volume 39)

Abstract

A form of cytochrome P-450 is produced in Saccharomyces cerevisiae during the logarithmic growth phase (14). This form is inhibited by metyrapone, tetrahydrofurane, and carbon oxide which are inhibitors of ethanolinducible cytochromes P-450 of mammals. Addition of Na-phenobarbital to the 0.5% glucose liquid medium induced a form of cytochrome P-450 inhibited only by metyrapone. Thus, yeast possess multiple forms of cytochrome P-450 that are individually inducible.

Keywords

Carbon Oxide Logarithmic Growth Phase Microsomal Cytochrome Post Mitochondrial Supernatant Mitotic Gene Conversion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • G. Bronzetti
    • 1
  • R. Del Carratore
    • 1
  1. 1.Istituto di Mutagenesi e Differenziamento CNRPisaItaly

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