Introduction: Avoidance of errors after DNA Damage

  • D. G. MacPhee
Part of the Basic Life Sciences book series (BLSC, volume 39)


Two of the following chapters are concerned with adaptive responses in Escherichia coli. Dr. Demple discusses possible mechanisms involved in the adaptive response to alkylation of DNA, and then describes several ways in which the response of E. coli cells to oxidative damage can be measured. In responding to an oxidative challenge, a novel type of adaptive response, different from either the SOS response or the heat shock response, appears to be involved.


Glycerol Caffeine Saccharomyces Ethionine 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Clarke, C.H. (1967) Caffeine- and amino acid-effects upon try+ revertant yield in UV-irradiated di-auxotrophs of E. coli B/r. Molec. Gen. Genet. 99:97–108.CrossRefGoogle Scholar
  2. 2.
    MacPhee, D.G. (1985) Indications that mutagenesis in Salmonella may be subject to catabolite repression. Mutat. Res. 151:35–41.CrossRefGoogle Scholar
  3. 3.
    Podger, D.M., G.W. Grigg, and D.G. MacPhee (1983) Ethionine abolishes mutagenesis by 9-aminoacridine (but not by 2-aminopurine) in Salmonella plate tests. Mutat. Res. 119:113–120.CrossRefGoogle Scholar
  4. 4.
    Shankel, D.M. (1962) Mutational synergism of ultraviolet light and caffeine in Escherichia coli. J. Bacteriol. 84:410–415Google Scholar

Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • D. G. MacPhee
    • 1
  1. 1.Department of MicrobiologyLa Trobe UniversityBundooraAustralia

Personalised recommendations