Morphometric Methods for the Evaluation of the Cochlear Microvasculature
Although the vasculature of the cochlea has been implicated in a number of etiologies of deafness, experimental verification for such an involvement has proved to be difficult; part of the reason for this difficulty is that, until recently, studies of the cochlear vasculature have been descriptive rather than quantitative. Descriptive studies have contributed significantly to our understanding of gross vascular pathology in the cochlea; however, it is difficult to document subtle morphological changes without resorting to quantitative methods. Since subtle changes in the blood supply to the cochlea may be involved in such clinical conditions as tinnitus, Meniere’s disease and temporary threshold shift following acoustic trauma, there has been considerable interest in developing quantitative methods for the analysis of the cochlear vasculature. Several such techniques are described in this chapter, following a brief review of the vascular anatomy of the cochlea.
KeywordsImpulse Noise Vessel Lumen Vascular Density Stria Vascularis Spiral Ligament
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