The Morphology of the Normal and Pathological Cell Membrane and Junctional Complexes of the Cochlea

  • Andrew Forge
Part of the NATO ASI Series book series (NSSA, volume 111)


Examination of the cell membranes in the cochlea is of some importance. Much of the normal functioning in the cochlea is dependent upon cell membrane properties and activities and on the presence of membrane specializations such as intercellular junctions. Further, there is evidence that in some forms of cochlear pathology effects on cell membranes are significant events. For example, the ototoxicity of aminoglycosides is thought to be related to specific interactions of the drugs with particular membrane lipids to produce alterations to membrane structure and function [1,2].


Tight Junction Hair Cell Apical Membrane Outer Hair Cell Lateral Membrane 


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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Andrew Forge
    • 1
  1. 1.Institute of Laryngology and OtologyLondonUK

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