Advertisement

NMR Studies of Base-Pair Kinetics of Nucleic Acids

  • Jean Louis Leroy
  • Daniel Broseta
  • Nicolas Bolo
  • Maurice Guéron
Part of the NATO ASI Series book series (NSSA, volume 110)

Abstract

The rate of exchange with water of the labile protons of a macromolecule may be connected with the rate of fluctuations which expose such protons to the solvent. The exchange process can be monitored by proton magnetic resonance which has the potential capability of identifying each exchangeable proton and of measuring its exchange rate.

Keywords

Exchange Rate Catalyst Concentration Magnetization Transfer Exchange Time Amino Proton 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Englander, S.W., Kallenbach, N.R. (1983) Q. Rev. Biophys. 16, 521–655.CrossRefGoogle Scholar
  2. 2.
    Teitelbaum, H. and Englander, S.W. (1975a) J. Mol. Biol. 92, 55–78.CrossRefGoogle Scholar
  3. 3.
    Teitelbaum, H. and Englander, S.W. (1975b) J. Mol, Biol. 92, 79–92.CrossRefGoogle Scholar
  4. 4.
    Mandai, C., Kallenbach, N.R. and Englander, S.W. (1979) J. Mol. Biol. 135, 391–411.CrossRefGoogle Scholar
  5. 5.
    Leroy, J.L., Bolo, N., Figueroa, N., Plateau, P. and Guéron, M. (1985) J. Biomol. Struct, and Dynam. 2, 915–939.Google Scholar
  6. 6.
    Leroy, J.L., Broseta, D. and Guéron, M. (1985) J. Mol. Biol. 184, 165–178.CrossRefGoogle Scholar
  7. 7.
    Granot, J., Assa-Munt, N. and Kearns, D.R. (1982) Biopolymers 21, 873–883.CrossRefGoogle Scholar
  8. 8.
    Caron, F., Guéron, M., Nguyen Ngoc Quoc, T. and Herzog, R.F. (1980) Rev. Phys. Appl. 15, 1267–1274.CrossRefGoogle Scholar
  9. 9.
    Plateau, P. and Guéron, M. (1982) J. Am. Chem. Soc. 104, 7310–7311.CrossRefGoogle Scholar
  10. 10.
    Morris, G.A. and Freeman, R. (1978) J. Mag. Res. 29, 433–462.CrossRefGoogle Scholar
  11. 11.
    Guéron, M. (1978) J. Mag. Res. 30, 515–520.CrossRefGoogle Scholar
  12. 12.
    Crothers, D.M., Cole, P.E., Hilbers, C.W. and Shulman, R.G. (1974) J. Mol. Biol. 82, 63–88.CrossRefGoogle Scholar
  13. 13.
    Johnston, P.D. and Redfield, A.G. (1978) Nucleic Acids Res. 5, 3913–3927.CrossRefGoogle Scholar
  14. 14.
    Mirau, P.A. and Kearns, D.R. (1984) J. Mol. Biol. 77, 207–221.CrossRefGoogle Scholar
  15. 15.
    Geerdes, H.A.M. and Hilbers, C.W. (1977) Nucleic Acids Res. 4, 207–221.CrossRefGoogle Scholar
  16. 16.
    Nakanishi, M. and Tsuboi, M. (1978) J. Mol. Biol. 124, 61–71.CrossRefGoogle Scholar
  17. 17.
    Neumann, J.M. and Tran-Dinh, S. (1981) Biopolymers 20, 89–106.CrossRefGoogle Scholar
  18. 18.
    Neumann, J.M. and Tran-Dinh, S. (1982) Biopolymers 21, 383–402.CrossRefGoogle Scholar
  19. 19.
    Eigen, M, (1964) Angew. Chem. Int. ed. Engl. 3, 1–19.CrossRefGoogle Scholar
  20. 20.
    Fritzsche, H., Kan, L.S., Ts’o, P.O.P. (1981) Biochemistry 20, 6118–6122.CrossRefGoogle Scholar
  21. 21.
    Izatt, R.M., Christensen, J.J. and Rytting, J.H. (1971) Chem. Rev. 71, 439–480.CrossRefGoogle Scholar
  22. 22.
    Handbook of Biochemistry and Molecular Biology, Physical and Chemical Data, 3rd edit, ed. Fassmann, G.D. (Cleveland, Ohio: Chemical Rubber Co.), p. 360.Google Scholar
  23. 23.
    Pörschke, D. (1971) Biopolymers 10, 1989–2013.CrossRefGoogle Scholar
  24. 24.
    Young, P.R. and Kallenbach, N.R. (1978) J. Mol. Biol. 126, 467–479.CrossRefGoogle Scholar
  25. 25.
    Quigley, G.J. and Rich, A. (1976) Science 194, 796–805.CrossRefGoogle Scholar
  26. 26.
    Englander, S.W., Kallenbach, N.R., Heeger, A.J., Krumhamsl, J.A. and Litwin, S. (1980) Proc.Natl. Acad. Sci. USA 77, 7222–7226.CrossRefGoogle Scholar
  27. 27.
    Figueroa, N., Keith, G., Leroy, J.L., Plateau, P., Roy, S. and Guéron, M. (1983) Proc. Natl. Acad. Sci. USA 80, 4330–4333.CrossRefGoogle Scholar
  28. 28.
    Fritzsche, H., Lou-Sing Kan and Tsfo, P.O.P. (1983) Biochemistry 23, 277–280.CrossRefGoogle Scholar
  29. 29.
    Mirau, P.A. and Kearns, D.R. (1985) Biopolymers 24, 711–724.CrossRefGoogle Scholar
  30. 30.
    Haasnoot, C.A.G., de Bruin, S.H., Berendsen, R.G., Janssen, H.G.J.M., Binnendijk, T.J.J., Hilbers, C.W., Van der Marel, G.A. and Van Boom, J.H. (1983) J. of Biomolecular Structure and Dynamics 1, 115–129.Google Scholar
  31. 31.
    Assa-Munt, N., Granot, J., Behling, R.W. and Kearns, D.R. (1984) Biochemistry 23, 944–955.CrossRefGoogle Scholar
  32. 32.
    Hurd, R.E. and Reid, B.R. (1980) J. Mol. Biol. 142, 181–193.CrossRefGoogle Scholar
  33. 33.
    Tropp, J.S. and Redfield, A.G. (1983) Nucleic Acids Res. 11, 2121–2133.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Jean Louis Leroy
    • 1
  • Daniel Broseta
    • 1
  • Nicolas Bolo
    • 1
  • Maurice Guéron
    • 1
  1. 1.Groupe de Biophysique du Laboratoire de Physique de la Matière CondenséeEcole PolytechniquePalaiseauFrance

Personalised recommendations