A Comparative Analysis of Structural Dynamics in 5S rRNA
A natural consequence of the discovery that several bacterial 5S rRNAs could be incorporated into active Bacillus stearothermophilus 50S subunits (Wrede and Erdmann, 1973) was the search for a common secondary structure for all bacterial 5S rRNAs. Fox and Woese (1975) were the first to suggest a base-pairing scheme based on sequence comparison. This secondary structure has, in the meantime, been confirmed by a spectrum of physical and biochemical investigations: proof enough of the strength of the sequence comparison approach.
KeywordsSingle Stranded Region Sodium Bisulphite Tertiary Interaction rRNA Species Common Secondary Structure
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