Molecular Dynamics Simulation of the Anticodon Arm of Phenylalanine Transfer RNA
Nucleic acid structures (Saenger, 1984), range from the classical double helices of A- and B-DNA, the detailed 3 D structures of crystalline tRNA (Kim et al., 1974; Ladner et al., 1975) to various DNA oligonucleotides in both left handed and right handed helical forms, for which there now is a wealth of experimental data (Saenger, 1984). This structural diversity has prompted numerous theoretical studies of the equilibrium properties of nucleic acids (see Olson, 1982, and references therein). By contrast only a very limited number of dynamical simulations of DNA (Levitt, 1983; Tidor et al., 1983) and tRNA (Harvey et al., 1984) have been reported.
KeywordsHydrogen Bond Length tRNA Molecule Anticodon Loop Nucleic Acid Structure Anisotropy Decay
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