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GU Base Pairs and Variable Loop in Yeast tRNAAsp

  • D. Moras
  • P. Dumas
  • E. Westhof
Part of the NATO ASI Series book series (NSSA, volume 110)

Abstract

Yeast tRNA(Asp) is an elongator tRNA with 4 bases in its variable loop. Few other features characterize its primary structure shown in Figure 1 together with that of yeast tRNA(Phe) (1,2); an exceptionally high GC content, 3 GU and one Gψ base pairs in three of its four stems and an almost self- complementary anticodon (GUC).

Keywords

Phosphorus Atom Variable Loop Yeast tRNA Purine Pyrimidine Helical Parameter 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Gangloff, J., Keith, G., Ebel, J.P. and Dirheimer, G. (1971). Nature New Biol. 230, 125–127.CrossRefGoogle Scholar
  2. 2.
    Rajbhandary, U. L. and Chang, S.H. (1968), J. Biol. Chem., 243, 598–608.Google Scholar
  3. 3.
    Moras, D., Comarmond, M. B., Fischer, J;, Weiss, R., Thierry, J.C., Ebel, J.P. and Giegé, R. (1980). Nature (London), 288, 669–674.CrossRefGoogle Scholar
  4. 4.
    Westhof, E., Dumas, P. and Moras, D. (1985) J. Mol. Biol., 184, 119–145.CrossRefGoogle Scholar
  5. 5.
    Sussman, J. L., Holbrook, S.R., Wade Warrant, R., Church, G.M. and Kim, S.H. (1978). J. Mol. Biol. 123, 607–630.CrossRefGoogle Scholar
  6. 6.
    Hingerty, B., Brown, R.S. and Jack, A. (1978). J. Mol. Biol. 124, 523–534.CrossRefGoogle Scholar
  7. 7.
    Stout, C.D., Mizuno, H., Rao, S.T., Swaminathan, P., Rubin, J., Brennan, T. and Sundaralingam, M. (1978). Acta Crystallogr. sect. B, 34, 1529–1544.CrossRefGoogle Scholar
  8. 8.
    Figueroa, N., Keith, G., Leroy, J.L., Plateau, P., Roy, F. and Gueron, M. (1983). Proc. Nat. Acad. Sci., U.S.A. 80, 4330–4333.CrossRefGoogle Scholar
  9. 9.
    Giegé, R., Romby, P., Florentz, C., Ebel, J.P., Dumas, P., Westhof, E. and Moras, D. (1983). In Nucleic Acids: The Vectors of Life (Pullman, B. and Jortner, J., eds), pp. 415–426, D. Reidel Publishing Company, Dordrecht.CrossRefGoogle Scholar
  10. 10.
    Romby, P., Moras D., Bergdoll M., Dumas P., Vlassov V.V., Westhof, E., Ebel, J.P. and Giegé, R. (1985) J. Mol. Biol. 184, 455–471.CrossRefGoogle Scholar
  11. 11.
    Arnott, S., Hukins, D. W., Dover, S.D., Fuller, W. and Hodgson, A.R. (1973). J. Mol. Biol. 81, 107–122.CrossRefGoogle Scholar
  12. 12.
    Jack, A., Ladner, J. E. and Klug, A. (1976). J. Mol. Biol. 108, 619–649.CrossRefGoogle Scholar
  13. 13.
    Holbrook, S.R., Sussman, J.L., Wade-Warrant, R. and Kim, S.H. (1978). J. Mol. Biol. 123, 631–660.CrossRefGoogle Scholar
  14. 14.
    Giegé, R., Moras, D. and Thierry, J.C. (1977). J. Mol. Biol. 115, 91–95.CrossRefGoogle Scholar
  15. 15.
    Yathindra, N. and Sundaralingam, M. (1976). Nucl. Acids Res. 3, 729–737.Google Scholar
  16. 16.
    Olson, W.K. (1981). In Biomolecular Dynamics (Sarma, R.H., ed.), pp. 327-336.Google Scholar
  17. 17.
    Mizuno, H. and Sundaralingam, M. (1978). Nucl. Acids Res. 5, 4451–4461.CrossRefGoogle Scholar
  18. 18.
    Grosjean, H.J., Cedergreen, R.J. and McKay, W. (1982). Biochimie. 64, 387–397.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • D. Moras
    • 1
  • P. Dumas
    • 1
  • E. Westhof
    • 1
  1. 1.Laboratoire de Cristallographie BiologiqueIBMC du CNRSStrasbourg cedexFrance

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