Inflammatory Lymphokines in Hypersensitivity Reactions

  • Marion C. Cohen
  • Janice K. Gutowski
  • Stanley Cohen


The immune system is responsible for both the detection of foreign substances and the response to them. Thus, immunologic function requires both recognition and reaction. Recognition involves the sequence of events by which the immune system is made aware of a foreign substance (antigen). It involves the interaction of the antigen with an appropriate cell surface receptor and leads to the activation of lymphocytes for both proliferation and differentiation. The products of differentiation include not only antibodies, but also memory cells, specialized effector cells, and a variety of nonantibody, hormonelike mediators. These latter agents, which have been shown to play a role in both afferent (inductive stages) and efferent (effector responses) manifestations of immunity, are known as lymphokines.


Migration Inhibition Factor Chemotactic Factor Delay Hypersensitivity Reaction Macrophage Migration Inhibition Leukocyte Inhibitory Factor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Marion C. Cohen
    • 1
  • Janice K. Gutowski
    • 1
  • Stanley Cohen
    • 1
  1. 1.Department of PathologyUniversity of Connecticut Health CenterFarmingtonUSA

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