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Fetal Blood Sampling and Fetoscopy

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Genetic Disorders and the Fetus

Abstract

The first endoscopic intrauterine visualization of the fetus was reported by Westin (1954). He inserted a 10-mm McCarthy panendoscope transcervically into the amniotic cavity in three patients undergoing midtrimester terminations of pregnancy and claimed adequate visualization of the fetus. No further reports appeared until 1969, when Scrimgeour proposed the term “fetoscopy,” for the endoscopic visualization of the fetus. Scrimgeour (1973) reported his experience with the use of a 2.2-mm fiberoptic endoscope at the time of hysterectomy in 19 patients also undergoing midtrimester terminations of pregnancy. He was also the first to use this procedure as a tool for antenatal diagnosis, reporting his results with fetoscopy in the antenatal diagnosis of six patients with a positive family history of severe central nervous system abnormalities (Scrimgeour, 1973). He correctly identified four fetuses as normal, was unable to enter the uterine cavity in one case, and considered normal an infant later delivered with spina bifida (Scrimgeour, 1973, 1976).

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Author information

Authors and Affiliations

  1. Departments of Obstetrics-Gynecology and Diagnostic Radiology, Yale University School of Medicine, New Haven, Connecticut, 06510, USA

    Roberto Romero & John C. Hobbins

  2. Departments of Human Genetics, Pediatrics, and Obstetrics-Gynecology, Yale University School of Medicine, New Haven, Connecticut, 06510, USA

    Maurice J. Mahoney

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  1. Roberto Romero
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  2. John C. Hobbins
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  3. Maurice J. Mahoney
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Editors and Affiliations

  1. Center for Human Genetics, Boston University School of Medicine, Boston, Massachusetts, USA

    Aubrey Milunsky MB.B.Ch., D.Sc., F.R.C.P., D.C.H. (Professor of Pediatrics, Obstetrics and Gynecology, and Pathology, Director) (Professor of Pediatrics, Obstetrics and Gynecology, and Pathology, Director)

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© 1986 Aubrey Milunsky

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Romero, R., Hobbins, J.C., Mahoney, M.J. (1986). Fetal Blood Sampling and Fetoscopy. In: Milunsky, A. (eds) Genetic Disorders and the Fetus. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5155-9_18

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  • DOI: https://doi.org/10.1007/978-1-4684-5155-9_18

  • Publisher Name: Springer, Boston, MA

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