Diagnosis of Fetal Abnormalities by Ultrasound

  • K. H. Nicolaides
  • S. Campbell


The introduction of ultrasound to obstetrics by Ian Donald in the 1950s is now regarded as one of the major milestones of modern medicine. Presently between 60 and 100% of mothers in Great Britain and other Western European countries have an ultrasound examination in the antenatal period, and the benefits in terms of accurate assessment of gestational age, verification of fetal viability, detection of multiple pregnancies, placental localization, and diagnosis of intrauterine growth retardation and fetal abnormalities are widely accepted. Despite recent publicity concerning possible adverse effects, there is no substantiated evidence of any deleterious biologic effects on mammalian tissues due to the low-intensity pulsed waves of ultrasound used for diagnostic purposes.


Amniotic Fluid Prenatal Diagnosis Congenital Diaphragmatic Hernia Spina Bifida Neural Tube Defect 
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Copyright information

© Aubrey Milunsky 1986

Authors and Affiliations

  • K. H. Nicolaides
    • 1
  • S. Campbell
    • 1
  1. 1.Department of Obstetrics and Gynaecology, Harris Birthright Research Centre for Fetal MedicineKing’s College School of Medicine and DentistryLondonEngland

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