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Treatment of Precocious Puberty with LHRH Agonists

A Pilot Study of the Efficiency of Periodic Administration of a Delayed-Release Preparation of D-Trp6-LHRH
  • Marc Roger
  • Jean-Louis Chaussain
  • Francoise Raynaud
  • Jean-Edmond Toublanc
  • Pierre Canlorbe
  • Jean-Claude Job
  • Andrew V. Schally
Part of the GWUMC Department of Biochemistry Annual Spring Symposia book series (GWUN)

Abstract

A better understanding of the paradoxical inhibitory effects of LHRH agonists has led to the discovery of new therapeutic agents, thanks largely to the experimental studies of Knobil’s group (Belchetz et al., 1978). Certain structural analogues have proven to be powerful suppressors of the pituitary-gonadal axis, as well as devoid of toxic effects.

Keywords

Precocious Puberty Pubic Hair Klinefelter Syndrome Cyproterone Acetate LHRH Agonist 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Marc Roger
    • 1
  • Jean-Louis Chaussain
    • 2
  • Francoise Raynaud
    • 2
  • Jean-Edmond Toublanc
    • 2
  • Pierre Canlorbe
    • 2
  • Jean-Claude Job
    • 2
  • Andrew V. Schally
    • 3
  1. 1.Fondation de Recherche en HormonologieFresnesFrance
  2. 2.Hôpital St. Vincent de PaulParisFrance
  3. 3.Veterans Administration Medical Center and Tulane University School of MedicineNew OrleansUSA

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