Neuropeptides and Adrenal Steroidogenesis

  • George V. Vahouny
  • Carol Herron
  • Robert Tombes
  • Terry W. Moody
Part of the GWUMC Department of Biochemistry Annual Spring Symposia book series (GWUN)


There has been a great deal of attention directed toward the source, regulation, and function of the peptides derived from the 31 -kD proadrenocorticotropin-endorphin precursor in the pituitary (Barker, 1977; Krieger, 1980; Numa and Nakanishi, 1980). The parent molecule is metabolized to an amino-terminal segment, referred to as the 16K fragment, the 39-amino-acid hormone ACTH, and a 91-amino-acid peptide, β-lipotropin (β-LPH). In turn, ACTH and β-LPH may be metabolized to the smaller peptides, including α-melanotropin (α-MSH) from ACTH and β-MSH and βendorphin from β-lipotropin.


cAMP Production Aldosterone Production Adrenal Steroidogenesis Steroidogenic Response Pituitary Peptide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • George V. Vahouny
    • 1
  • Carol Herron
    • 1
  • Robert Tombes
    • 1
  • Terry W. Moody
    • 1
  1. 1.Department of BiochemistryThe George Washington University School of Medicine and Health SciencesUSA

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