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Neural and Endocrine Peptides and Receptors pp 3–13Cite as

An Endogenous Peptide Ligand for the PCP/σ-Opiod Receptor

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Abstract

Opioid receptors comprise a heterogeneous group that can be divided into at least four biochemically and topographically distinct subtypes, designated (μ, κ, σ, and δ. Martin et al. (1976) proposed the existence of μ-, κ-, and α-opioid receptors based on observed differences in pharmacological profiles of drugs seen with variably selective opioid agonists and antagonists. Other groups have provided evidence for the 8 subtype (Hughes et al., 1975).

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Author information

Authors and Affiliations

  1. Experimental Therapeutics Branch, National Institute of Neurological and Communicative Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, 20205, USA

    Patricia C. Contreras

  2. Department of Medicine, Howard University, Washington, D. C., 20059, USA

    Patricia C. Contreras

  3. Experimental Therapeutics Branch, National Institute of Neurological and Communicative Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, 20205, USA

    Debora A. Dimaggio & Thomas L. O’Donohue

  4. Douglas Hospital Research Centre, McGill University, Verdun, Quebec, H4H 1R3, Canada

    Rémi Quirion

  5. Department of Psychiatry, Faculty of Medicine, McGill University, Verdun, Quebec, H4H 1R3, Canada

    Rémi Quirion

Authors
  1. Patricia C. Contreras
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  2. Debora A. Dimaggio
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  3. Thomas L. O’Donohue
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  4. Rémi Quirion
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Editor information

Editors and Affiliations

  1. The George Washington University School of Medicine and Health Sciences, Washington, D.C., USA

    Terry W. Moody

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© 1986 Plenum Press, New York

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Contreras, P.C., Dimaggio, D.A., O’Donohue, T.L., Quirion, R. (1986). An Endogenous Peptide Ligand for the PCP/σ-Opiod Receptor. In: Moody, T.W. (eds) Neural and Endocrine Peptides and Receptors. GWUMC Department of Biochemistry Annual Spring Symposia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5152-8_1

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  • DOI: https://doi.org/10.1007/978-1-4684-5152-8_1

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  • Print ISBN: 978-1-4684-5154-2

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