An Endogenous Peptide Ligand for the PCP/σ-Opiod Receptor
Opioid receptors comprise a heterogeneous group that can be divided into at least four biochemically and topographically distinct subtypes, designated (μ, κ, σ, and δ. Martin et al. (1976) proposed the existence of μ-, κ-, and α-opioid receptors based on observed differences in pharmacological profiles of drugs seen with variably selective opioid agonists and antagonists. Other groups have provided evidence for the 8 subtype (Hughes et al., 1975).
KeywordsOpioid Receptor Opioid Peptide Stereotyped Behavior Endogenous Ligand Opiate Receptor
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