Kinins IV pp 291-297 | Cite as

The Tissue Kallikrein-Kinin System in Human Seminal Plasma — Biochemical and Functional Aspects

  • Edwin Fink
  • Wolf-Bernhard Schill
  • Franz Fiedler
  • Kazuaki Shimamoto
  • Franz Krassnigg
  • Julian Frick
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 198A)


At least three species of tissue kaliikrein-like antigens are present in human seminal plasma which differ in their molecular masses and enzymatic activities. At least one of these species is a genuine tissue kallikrein as judged by the criteria of molecular mass, immunoreactivity, inhibition by aprotinin and non-inhibition by soybean trypsin inhibitor, and the ability to release kallidin from kininogen. The prostatic gland was identified as the origin of the seminal fluid tissue kallikrein first by indirect studies and then by demonstrating the presence of immunoreactive tissue kallikrein both in prostatic tissue and secretion.


Prostate Gland Seminal Plasma Soybean Trypsin Inhibitor Tissue Kallikrein Prostatic Secretion 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Edwin Fink
    • 1
  • Wolf-Bernhard Schill
    • 2
  • Franz Fiedler
    • 1
  • Kazuaki Shimamoto
    • 3
  • Franz Krassnigg
    • 2
  • Julian Frick
    • 4
  1. 1.Abteilung für Klinische Chemie und Klinische Biochemie in der Chirurgischen Klinik InnenstadtUniversität MünchenGermany
  2. 2.Dermatologische Klinik und PoliklinikLudwig-Maximilians Universität MünchenGermany
  3. 3.The Second Department of Internal MedicineSapporo Medical CollegeJapan
  4. 4.Urologische AbteilungLandeskrankenhaus SalzburgAustria

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