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Kinins IV pp 91-95 | Cite as

Amino Acid Sequence of the Light Chain of Human Low Molecular Mass Kininogen

  • Friedrich Lottspeich
  • Josef Kellermann
  • Agnes Henschen
  • Günther Rauth
  • Werner Müller-Esterl
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 198A)

Summary

The light chain of human low molecular mass kininogen consists of 38 amino acid residues. The half-cystine residue which forms the disulfide bridge to the heavy chain is located in the position 18. Alignment of the low molecular mass kininogen light chain with corresponding sections of other kininogens revealed that the N-terminal part of it is species specific and the C-terminal part is function specific. Furthermore, some internal homologies between various sections of the total molecule were found. A statistically significant sequence homology between the low molecular mass kininogen light chain and the C-terminal part of the ribonucleases was observed.

Keywords

Amino Acid Residue Light Chain Heavy Chain Amino Acid Analysis Disulfide Bridge 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Friedrich Lottspeich
    • 1
    • 2
  • Josef Kellermann
    • 1
    • 2
  • Agnes Henschen
    • 1
    • 2
  • Günther Rauth
    • 1
    • 2
  • Werner Müller-Esterl
    • 1
  1. 1.Max-Planck-Institut für BiochemieMartinsriedDeutschland
  2. 2.Abteilung für Klinische Chemie und BiochemieUniversität MünchenMünchenDeutschland

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