Contraceptive Effect of Two Anti-Sperm Monoclonal Antibodies, Administered Singly and in Combination, in the Mouse
Although many reports in the literature suggest an association between infertility and anti-sperm antibodies, the particular sperm antigens) that may be responsible is unknown. In an effort to sort out this dilemma, as well as to identify sperm components involved specifically at discrete steps of the gamete interaction process, we have generated antimouse sperm monoclonal antibodies (mAbs).
KeywordsPassive Immunization Tubal Lumen Mouse Sperm Contraceptive Vaccine Sperm Penetration
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