Biological Reactive Metabolites in Human Toxicity

  • Hermann M. Bolt
  • Hans Peter
  • Hans-Jürgen Wiegand
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 197)


Accidental exposures of employees to some acutely and chronically toxic industrial chemicals have brought up the question of effectiveness of antidotes which may facilitate detoxication. Because of recent severe (Vogel and Kirkendall, 1984) or even fatal (BG Chemie, 1980) accidents initial emphasis was focussed on acrylonitrile. Later, the investigations also included methacrylonitrile, methyl bromide, and chromates.


Hexavalent Chromium Methyl Bromide Hepatic Microsome Bromide Methyl Methyl Chloride 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Hermann M. Bolt
    • 1
  • Hans Peter
    • 1
  • Hans-Jürgen Wiegand
    • 1
  1. 1.Institut für ArbeitsphysiologieUniversität DortmundDortmund 1Germany

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