The use of an LHRH Agonist in the Treatment and Investigation of the Premenstrual Syndrome

  • John Bancroft
  • Harry Boyle
  • Hamish Fraser
Part of the Biochemical Endocrinology book series (BIOEND)


The premenstrual syndrome (PMS) remains an enigma. It has as yet eluded satisfactory definition+. The symptoms are protean, involving psychological states such as irritability, depression, tiredness, feelings of abdominal bloatedness, tender swollen breasts, headaches, appetite change, especially carbohydrate craving, changes in bowel and bladder function, allergic reactions, acne, reduced resistance to infections and others. Their temporal relationship with the menstrual cycle is also variable, though symptoms are usually confined to the second half of the cycle declining soon after the onset of menstruation.


Ovarian Cycle Menstrual Bleeding Ovarian Activity Premenstrual Syndrome LHRH Agonist 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • John Bancroft
    • 1
  • Harry Boyle
    • 2
  • Hamish Fraser
    • 1
  1. 1.MRC Reproductive Biology UnitEdinburghUK
  2. 2.Reproductive Endocrinology LaboratoriesEdinburghUK

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