Ion Channels and the Control of Secretion in Normal Anterior Pituitary Cells
Secretion of the anterior pituitary hormones is controlled by peptides and amines synthesized and released by discrete neurones in the hypothalamus. The action of these factors in regulating hormone release is believed to involve changes in the electrical activity of the specific target cells (Douglas and Taraskevich, 1985). Because of the exceptional variety of different hormone-containing cell types in the anterior pituitary gland, most knowledge about the membrane properties which might be important in the regulation of hormone secretion from these cells has been derived from work using pituitary tumour cell lines as models.
KeywordsPituitary Cell Rest Membrane Potential Intracellular Recording Anterior Pituitary Cell Membrane Patch
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