Lessons for Muscle Energetics from 31P NMR Spectroscopy

  • Martin J. Kushmerick
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 194)


The basic paradigm of muscle energetics has two aspects: (1) there is a net decrease in chemical potential energy content during muscular activity, the net reaction being the splitting of PCr; and (2) there is a recovery period after mechanical relaxation in which oxidative metabolism uses substrate to regenerate the initial pre-contraction steady-state levels of high-energy phosphate compounds, and so restores the initial chemical potential. At least under certain experimental conditions, it is possible to separate completely the processes occurring in the contraction phase (e.g., PCr splitting) from those occurring in the recovery phase (e.g., oxygen consumption above the basal rate).


Creatine Kinase Soleus Muscle Extensor Digitorum Longus Contractile Activity Creatine Kinase Reaction 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Martin J. Kushmerick
    • 1
  1. 1.Division of Nuclear Magnetic Resonance Department of RadiologyHarvard Medical SchoolBostonUSA

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