Differential Regulation of Specific Gene Expression in Mouse Kidney by Androgens and Antiandrogens
Androgens, as other steroid hormones, interact with a receptor protein to regulate gene expression in target tissues.1 Much of the work to date on this subject has involved analysis of the abundant gene products stimulated by androgens in the rat prostate2,3 and seminal vesicle.4–6 However, no attempts were made in these studies to correlate specific gene expression with androgen receptor dynamics or to compare the androgen sensitivity of these different genes in male accessory sex organs.
KeywordsAndrogen Receptor Ornithine Decarboxylase Mouse Kidney mRNA Concentration Receptor Concentration
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