Development of the Peripheral Nervous System from the Neural Crest: Aspects of Cell Line Segregation and Differentiation

  • Julian Smith
  • Nicole M. Le Douarin
Part of the NATO ASI Series book series (NSSA, volume 99)


The neural crest, which originates from the lateral ridges of the neural primordium in the Vertebrate embryo, constitutes a useful model for the study of a number of important developmental processes, including cell migration and differentiation. All the peripheral nervous system, apart from certain cranial sensory ganglia, is derived from the neural crest, and much interest currently centres on the mechanisms whereby a wide variety of differentiated cell types emerges from a structure that is, by classical cytological criteria, apparently homogenous.


Neural Crest Peripheral Nervous System Neural Crest Cell Glyoxylic Acid Autonomic Neuron 
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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Julian Smith
    • 1
    • 2
  • Nicole M. Le Douarin
    • 1
    • 2
  1. 1.Institut d’Embryologie du CNRSNogent-sur-MarneFrance
  2. 2.Collège de FranceNogent-sur-MarneFrance

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