Advertisement

The Adhesions of Epithelial Cells

  • D. R. Garrod
Part of the NATO ASI Series book series (NSSA, volume 99)

Abstract

Epithelia are tissues which line or cover the cavities and surfaces of the bodies of animals. They consist of single or stratified sheets of cells which are applied to be underlying tissue on one face, the basal surface, and have a free edge adjacent to a luminal space on the other face, the apical surface. All epithelia thus have a structural apico-basal polarity which is always of great functional importance. For example, in absorptive epithelia such as that of the small intestine, absorption takes place at the apical surface of the cells and the absorbed material is transported basally. In protective epithelia such as the epidermis, the apical surface must be strong in order to resist friction and pressure, while the basal region of the epithelium must generate new cells to replace the stressed apical tissue.

Keywords

Corneal Epithelial Cell Adhesion Mechanism Focal Contact MDBK Cell Simple Epithelium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    M. Abercrombie and G.A. Dunn, Exp. Cell Res., 92: 57–62 (1975).PubMedCrossRefGoogle Scholar
  2. 2.
    A. Allen, R. Dulbecco, P. Syka and M. Bowman, Proc. Natl. Acad. Sci. USA (in press) (1984).Google Scholar
  3. 3.
    P.C. Baker and T.E. Schroeder, Dev. Biol., 15: 432 (1967).PubMedCrossRefGoogle Scholar
  4. 4.
    H. Bentz, N.P. Morris, L.W. Murray, L.Y. Sakai, D.W. Hollister and R.E. Burgeson, Proc. Natl. Acad. Sci. USA, 80: 3168–3172 (1983).CrossRefGoogle Scholar
  5. 5.
    D. Billig, A. Nicol, R. McGinty, P. Cowin, J. Morgan and D. Garrod, J. Cell Sci., 57: 51–71 (1982).PubMedGoogle Scholar
  6. 6.
    J.Z. Borysenko and J.P. Revel, J. Anat., 137: 403–422 (1973).CrossRefGoogle Scholar
  7. 7.
    A. Bretscher, J. Cell Biol., 97: 425–432 (1983).PubMedCrossRefGoogle Scholar
  8. 8.
    R.A. Briggaman and C.E. Wheeler, J. invest. Dermatol., 65: 71–84 (1975).PubMedCrossRefGoogle Scholar
  9. 9.
    S.S. Brown, H.L. Malinoff and M.S. Wicha, Proc. Natl. Acad. Sci. USA, 80: 5927–5930 (1983).CrossRefGoogle Scholar
  10. 10.
    D.R. Burgess, J. Cell Biol., 95: 853–863 (1982).PubMedCrossRefGoogle Scholar
  11. 11.
    K. Burridge and P. Mangeat, Nature, 308: 744–746 (1984).PubMedCrossRefGoogle Scholar
  12. 12.
    E. Christophers and H.H. Wolf, Nature, 256: 209–210 (1975).PubMedCrossRefGoogle Scholar
  13. 13.
    S.M. Cohen, G. Gorbsky and M.S. Steinberg, J. Biol. Chem., 90: 243–248 (1983).Google Scholar
  14. 14.
    C.A.L.S. Colaco and W.H. Evans, J. Cell Sci., 52: 313–325 (1981).PubMedGoogle Scholar
  15. 15.
    C.A.L.S. Colaco and W.H. Evans, Electron Microscopy of Proteins, 4: 332–363 (1983).Google Scholar
  16. 16.
    P. Cowin and D.R. Garrod, Nature, 302: 148–150 (1983).PubMedCrossRefGoogle Scholar
  17. 17.
    P. Cowin, D.L. Mattey and D.R. Garrod, J. Cell Sci., 66: 119–132 (1984 a).PubMedGoogle Scholar
  18. 18.
    P. Cowin, D.L. Mattey and D.R. Garrod, J. Cell Sci., (in press) (1984 b).Google Scholar
  19. 19.
    S.W. Craig and J.V. Pardo, J. Cell Biol., 80: 203–210 (1979).PubMedCrossRefGoogle Scholar
  20. 20.
    A.S.G. Curtis, J. Cell Biol., 20: 199–215 (1964).PubMedCrossRefGoogle Scholar
  21. 21.
    C.H. Damsky, J. Richa, D. Solter, K. Knudsen and C.A. Buck, Cell, 34: 455–466 (1983).PubMedCrossRefGoogle Scholar
  22. 22.
    H.M. Dembitzer, F. Herz, A. Schermer, R.C. Wooley and L.G. Koss, J. Cell Biol., 85: 695–702 (1980).PubMedCrossRefGoogle Scholar
  23. 23.
    R.J. Doherty, J.G. Edwards, D.R. Garrod and D.L. Mattey, J. Cell Sci., (in press) (1984).Google Scholar
  24. 24.
    P. Drochmans, C. Freudenstein, J.C.Wanson, L. Laurent, T.W. Keenan, J. Stadler, R. Leloup and W. Franke, J. Cell Biol., 80: 231–247 (1978).Google Scholar
  25. 25.
    T. Ducibella, D.F. Albertini, E. Anderson and J.D. Biggers, Dev. Biol., 45: 231–250 (1975).PubMedCrossRefGoogle Scholar
  26. 26.
    R. Dulbecco, W.R. Allen and M. Bowman, Proc. Natl. Acad. Sci. USA, (in press) (1984).Google Scholar
  27. 27.
    G.M. Edelman, Science, 219: 450–457 (1983).PubMedCrossRefGoogle Scholar
  28. 28.
    J.E. Ellison and D.R. Garrod, J. Cell Sci., (in press) (1984).Google Scholar
  29. 29.
    R.M. Färb, R. Dykes and G.S. Lazarus, Proc. Natl. Acad. Sci. USA, 75: 459–463 (1978).CrossRefGoogle Scholar
  30. 30.
    M.G. Farquhar and G. Palade, J. Cell Biol., 19: 375–412 (1963).CrossRefGoogle Scholar
  31. 31.
    W.W. Franke, H.P. Kaprell and H. Mueller, Eur. J. Cell Biol., 32: 117–130 (1983).PubMedGoogle Scholar
  32. 32.
    W.W. Franke, R. Moll, D.L. Schiller, E. Schmid, J. Kartenbeck and H. Mueller, Differentiation, 23: 115–127 (1982).PubMedCrossRefGoogle Scholar
  33. 33.
    W.W. Franke, E. Schmid, C. Grund, H. Mueller, I. Engelbrecht, R. Moll, J. Stadler and E.D. Jarasch, Differentiation, 20: 217–241 (1981).PubMedCrossRefGoogle Scholar
  34. 34.
    D.R. Garrod, Fortschritter der Zoologie, 26: 184–195 (1981).Google Scholar
  35. 35.
    D.R. Garrod and P. Cowin, In: “Receptors in Tumour Biology”, ed. C.M. Chadwick (in press) (1984).Google Scholar
  36. 36.
    D.R. Garrod and A. Nicol, Biol. Rev., 56: 199–242 (1981).PubMedCrossRefGoogle Scholar
  37. 37.
    B. Geiger, A.H. Dutton, K.T. Tokuyasu and S.J. Singer, J. Cell Biol., 91: 614–628 (1981).PubMedCrossRefGoogle Scholar
  38. 38.
    B. Geiger, E. Schmid and W.W. Franke, Differentiation, 23: 189–205 (1983).PubMedCrossRefGoogle Scholar
  39. 39.
    B. Geiger, K.T. Tokuyasu, A.H. Dutton and S.J. Singer, Proc. Natl. Acad. Sci. USA, 77: 4127–4131 (1980).CrossRefGoogle Scholar
  40. 40.
    B.M. Geiger, K.T. Tokuyasu and S.J. Singer, Proc. Natl. Acad. Sci. USA, 76: 2833–2837 (1979).CrossRefGoogle Scholar
  41. 41.
    N.B. Gilula, In: “Intercellular Junctions and Synapses”, ed. J. Feldman, N.B. Gilula and J.D. Pitts, ( Chapman and Hall, London ), pp. 1–22 (1978).Google Scholar
  42. 42.
    I.K. Gipson, M.S. Grill, S.J. Spurr and S.J. Brennan, J. Cell Biol., 97: 849–857 (1983).PubMedCrossRefGoogle Scholar
  43. 43.
    G. Gorbsky, S. Cohen and M.S. Steinberg, J. invest. Dermatol., 80: 475–480 (1983).PubMedCrossRefGoogle Scholar
  44. 44.
    G. Gorbsky and M.S. Steinberg, J. Cell Biol., 90: 243–248 (1981).PubMedCrossRefGoogle Scholar
  45. 45.
    H. Green, O. Kehinde and J. Thomas, Proc. Natl. Acad. Sci. USA, 76: 5665–5668 (1979).CrossRefGoogle Scholar
  46. 46.
    J.P. Heath, In: “Cell Behaviour”, ed. R. Bellairs, A.S.G. Curtis and G.A. Dunn, ( Cambridge University Press ), pp. 77–108 (1982).Google Scholar
  47. 47.
    J.P. Heath and G.A. Dunn, J. Cell Sci., 29: 197–212 (1978).PubMedGoogle Scholar
  48. 48.
    D. Henderson and K. Weber, Exp. Cell Res., 132: 297–311 (1981).PubMedCrossRefGoogle Scholar
  49. 49.
    H. Hennings and K. Holbrook, Exp. Cell Res., 143: 127–142 (1983).PubMedCrossRefGoogle Scholar
  50. 50.
    H. Hennings, K.A. Holbrook and S.H. Yuspa, J. Cell Physiol., 116: 265–281 (1983 a).PubMedCrossRefGoogle Scholar
  51. 51.
    H. Hennings, K.A. Holbrook and S.H. Yuspa, J. invest. Dermatol., 81: 50s–55s (1983 b).CrossRefGoogle Scholar
  52. 52.
    H. Hennings, D. Michael, C. Cheng, P. Steinert, K. Holbrook and S.H. Yuspa, Cell, 19: 245–254 (1980).PubMedCrossRefGoogle Scholar
  53. 53.
    D.A. Herzlinger and G.K. Ojakian, J. Cell Biol., 98: 1777–1787 (1984).PubMedCrossRefGoogle Scholar
  54. 54.
    C.S. Izzard and L.R. Lochner, J. Cell Sci., 21: 129–159 (1976).PubMedGoogle Scholar
  55. 55.
    M.A. Jakus, Invest. Ophtalmol., 1: 202–225 (1962).Google Scholar
  56. 56.
    J.C.R. Jones, J. Arun, L.A. Staehelin and R.D. Goldman, Proc. Natl. Acad. Sci. USA, 81: 2781–2785 (1984).PubMedCrossRefGoogle Scholar
  57. 57.
    P. Karfunkel, Dev. Biol., 25: 30 (1971).PubMedCrossRefGoogle Scholar
  58. 58.
    J. Kartenbeck, W.W. Franke, J.G. Moser and U. Stoffels, EMBO J, 2: 735–742 (1983).PubMedGoogle Scholar
  59. 59.
    J. Kartenbeck, E. Schmid, W.W. Franke and B. Geiger, EMBO J., 1: 725–732 (1982).PubMedGoogle Scholar
  60. 60.
    J. Kartenbeck, K. Schwechleimer, R. Moll and W.W. Franke, J. Cell Biol., 98: 1072–1081 (1984).PubMedCrossRefGoogle Scholar
  61. 61.
    D.E. Kelly, J. Cell Biol., 28: 51–73 (1966).PubMedCrossRefGoogle Scholar
  62. 62.
    M.W. Klymkowsky, R.H. Miller and E.B. Lane, J. Cell Biol., 96: 494–509 (1983).PubMedCrossRefGoogle Scholar
  63. 63.
    W.S. Krawczyk and G.F. Wilgram, J. Ultrastruct. Res., 45: 93–101 (1973).PubMedCrossRefGoogle Scholar
  64. 64.
    E.B. Lane, J. Cell Biol., 92: 665–673 (1982).PubMedCrossRefGoogle Scholar
  65. 65.
    N.J. Lane, In: “Electron Microscopy” Vol. 3, State of the Art Symposia ed. J.M. Sturgess, (Imperial Press, Toronto), pp. 673–691 (1978).Google Scholar
  66. 66.
    T.L. Lentz and J.P. Trinkaus, J. Cell Biol., 48: 455–472 (1971).PubMedCrossRefGoogle Scholar
  67. 67.
    H.L. Malinoff and M.S. Wicha, J. Cell Biol., 96: 1475–1479 (1983).PubMedCrossRefGoogle Scholar
  68. 68.
    D.L. Mattey and D.R. Garrod, J. Cell Sci., 67: 171–188 (1984a).PubMedGoogle Scholar
  69. 69.
    D.L. Mattey and D.R. Garrod, J. Cell Sci., 67: 189–202 (1984b).PubMedGoogle Scholar
  70. 70.
    D.L. Mattey and D.R. Garrod, in preparation, (1984 c).Google Scholar
  71. 71.
    N.S. McNutt and R.S. Weinstein, Prog. Biophys. Mol. Biol., 26: 45–101 (1976).CrossRefGoogle Scholar
  72. 72.
    J. Mollenhauer and K. von der Mark, EMBO J., 2: 45–50 (1983).PubMedGoogle Scholar
  73. 73.
    J. Morgan and D.R. Garrod, J. Cell Sci., 66: 133–145 (1984).PubMedGoogle Scholar
  74. 74.
    H. Mueller and W.W. Franke, J. mol. Biol., 163: 647–671 (1983).PubMedCrossRefGoogle Scholar
  75. 75.
    A. Nicol and D.R. Garrod, J. Cell Sci., 54: 357–372 (1982).PubMedGoogle Scholar
  76. 76.
    C. Ocklind, U. Forsum and D. Obrink, J. Cell Biol., 96: 1168–1171 (1983).PubMedCrossRefGoogle Scholar
  77. 77.
    B. Oesch and W. Birchmeier, Cell, 31: 671–679 (1982).PubMedCrossRefGoogle Scholar
  78. 78.
    S.I. Ogou, G. Yoshida-Noro and M. Takeichi, J. Cell Biol., 97: 944–948 (1983).PubMedCrossRefGoogle Scholar
  79. 79.
    J. Overton, J. exp. Zool., 168: 203–214 (1968).PubMedCrossRefGoogle Scholar
  80. 80.
    J. Overton, Prog. Surf. Sci., 8: 161–208 (1974).Google Scholar
  81. 81.
    J. Overton, Dev. Biol., 55: 103–116 (1977).PubMedCrossRefGoogle Scholar
  82. 82.
    G.E. Palade and M.G. Farquhar, J. Cell Biol., 27: 215–224 (1965).PubMedCrossRefGoogle Scholar
  83. 83.
    N.C. Rao, S.H. Barsky, V.P. Terranova and L.A. Liotta, Biochem. Biophys. Res. Commun., 111: 804–808 (1983).CrossRefGoogle Scholar
  84. 84.
    D.G. Rayns, F.O. Simpson and J.M. Ledingham, J. Cell Biol., 42: 322–326 (1969).PubMedCrossRefGoogle Scholar
  85. 85.
    D.A. Rees, R.A. Badley, C.E. Lloyd, D. Thomn and C.G. Smith, In: “Cell-cell Recognition” 32 nd. Symp. Soc. Exp. Biol. ed. A.S.G. Curtis, (Cambridge University Press, Cambridge), pp. 241–260 (1978).Google Scholar
  86. 86.
    L.A. Represh and J.C. Oberpriller, Am. J. Anat., 159: 187–208 (1980).CrossRefGoogle Scholar
  87. 87.
    J.G. Rheinwald and H. Green, Cell, 6: 331–344 (1975).PubMedCrossRefGoogle Scholar
  88. 88.
    K. Rubin, M. Hook, B. Obrink and R. Timpl, Cell, 24: 463–470 (1981).PubMedCrossRefGoogle Scholar
  89. 89.
    I.I. Singer, J. Cell Biol., 92: 398–408 (1982).PubMedCrossRefGoogle Scholar
  90. 90.
    C.J. Skerrow and G.A. Matoltsy, J. Cell Biol., 63: 515–523 (1974).PubMedCrossRefGoogle Scholar
  91. 91.
    L.A. Staehelin, Int. Rev. Cytol., 39: 191–283 (1974).PubMedCrossRefGoogle Scholar
  92. 92.
    M.S. Steinberg, In: “Cellular Membranes in Development” ed. M. Locke, ( Academic Press, New-York ), pp. 321–366 (1964).Google Scholar
  93. 93.
    M.S. Steinberg, J. Exp. Zool., 173: 395–434 (1970).PubMedCrossRefGoogle Scholar
  94. 94.
    M.S. Steinberg, In: “Specificity of Embryological Interactions” ed. D.R. Garrod, (Chapman and Hall, London), pp. 99–130 (1978 a).Google Scholar
  95. 95.
    M.S. Steinberg, In: “Cell-cell Recognition” 32 nd Symp. Soc. Exp. Biol. ed. A.S.G. Curtis, (Cambridge University Press, Cambridge), pp. 25–49 (1978 b).Google Scholar
  96. 96.
    M. Stoker, J. Cell Physiol., (in press) (1984).Google Scholar
  97. 97.
    S.P. Sugrue and E.D. Hay, Dev. Biol., 92: 97–106 (1982).PubMedCrossRefGoogle Scholar
  98. 98.
    A. Suhrbier and D.R. Garrod, in preparation, (1984).Google Scholar
  99. 99.
    L.G. Tilney and M.S. Mooseker, Proc. Natl. Acad. Sci. USA, 68: 2611–2615 (1971).CrossRefGoogle Scholar
  100. 100.
    V. Trinkaus-Randall and I.K.Gipson, J. Cell Biol., 98: 1565–1571 (1984).PubMedCrossRefGoogle Scholar
  101. 101.
    F.M. Watt and H. Green, Nature, 295: 434–436 (1982).PubMedCrossRefGoogle Scholar
  102. 102.
    F.M. Watt, D.M. Mattey and D.R. Garrod, J. Cell Biol., (in press) (1984).Google Scholar
  103. 103.
    R.S. Weinstein, F.B. Merk and J. Al’roy, Adv. Cancer Res., 23: 23–89 (1976).PubMedCrossRefGoogle Scholar
  104. 104.
    L.L. Wiseman and J. Strickler, J. Cell Sci., 49: 217–224 (1981).PubMedGoogle Scholar
  105. 105.
    A. Woods, M. Hook, L. Kjellen, C.G. Smith and D.A. Rees, J. Cell Biol., (in press) (1985).Google Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • D. R. Garrod
    • 1
  1. 1.Cancer Research Campaign Medical Oncology Unit, CF99Southampton General HospitalSouthamptonUK

Personalised recommendations