Relation between Structure and Function of Gap Junctions
It has become clear over the past fifteen years that the cells in organized tissues commonly form interconnected systems. The cell-to-cell interaction arises when the plasma membrane of individual cells contact each other. At the level of these contacts a specialization of the cell surface takes place, which exhibits various structural differentiations depending on the cell-to-cell interaction. The name gap junction is now widely accepted for the cell-to-cell interaction where the two adjacent cells can exchange part of their molecular content (metabolic coupling) or different ions (ionic coupling). Several reviews have been published on the structural and functional aspects of the gap junction (1–2–3).
KeywordsJunctional Conductance Junctional Membrane Electrical Uncouple Junctional Particle Junctional Unit
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