Experimental Models for in Vivo and in Vitro Investigations on Placental Hemodynamics and Oxygen Supply to the Fetus
Gas exchange across the placenta is for obvious reasons of the utmost interest to all obstetricians and pediatricians, placental transfer of oxygen being essential to keep the fetus alive and to promote its development. Theoretic models have been constructed lately to represent respiratory gas transfer in the complex intrauterine environment using mainly physiological parameters obtained by using “chronic preparations,” thus avoiding the adverse effects of surgical manipulation or of anesthesia which produce important hemodynamic changes in the extremely sensitive umbilical or uterine vasculatures.
KeywordsPlacental Transfer Uterine Blood Flow Placental Perfusion Placental Circulation Perinatal Brain Damage
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