Effect of Carbonic Anhydrase on the Facilitated Diffusion of CO2 through Bicarbonate Solutions
Over the last 10 years, several groups have given experimental evidence that carbon dioxide diffusion in aqueous solutions can be augmented by the presence of base, buffers, and catalysts for the hydration reaction of carbon dioxide with water (1,2,3). Although the mechanism for this augmentation has been presumed to be a carrier type of facilitation, no previous experimental study has covered a wide range of facilitation factors (augmented flux/ Fick’s Law flux) and at the same time presented a solution to the mathematical model which can be used to calculate the expected transport rates. This paper summarizes some of our efforts in this direction.
KeywordsCarbonic Anhydrase Reaction Invariant Damkohler Number Carbon Dioxide Reaction Facilitation Factor
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