An Analysis of the Competitive Diffusion of O2 and Co through Hemoglobin Solutions

  • S. R. Suchdeo
  • J. D. Goddard
  • J. S. Schultz
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 191)


The subject of carrier-mediated or “facilitated” transport has received widespread attention in the chemical and biological literature, especially in conjunction with diffusion across thin films or membranes. One of the simpler conceptual models for the phenomenon is based on the postulate of ordinary molecular diffusion coupled with reversible homogeneous chemical reactions. The diffu-sional flux of a transferred chemical species is thereby “mediated” or altered by reversible combination with certain mobile “carrier” species which are indigenous to the film or membrane. Any such species, which is physically restricted to the carrier-mediated transport system, will be designated here as a “non-volatile” or “non-transferred” species.


Tissue Oxygenation Reaction Layer Hemoglobin Solution Transmembrane Flux Simple Conceptual Model 
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Copyright information

© Plenum Press, New York 1973

Authors and Affiliations

  • S. R. Suchdeo
    • 1
  • J. D. Goddard
    • 1
  • J. S. Schultz
    • 1
  1. 1.Department of Chemical EngineeringUniversity of MichiganAnn ArborUSA

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