Kinetic Models and Channel Fluctuations
In this chapter the essentials of the kinetics of opening and closing of ionic channels will be discussed. I present several kinetic models and show the type of single channel records to be expected for each model and how to calculate kinetic constant from these records. The models I discuss are two state channels, three-state channels with three conductances, and three-state channels with only two conductances. The basic ideas for this chapter were taken from Dionne and Leibowitz (1982) and Ehrenstein et al. (1974).
KeywordsOpen Channel Closed State Closed Time Current Record Record Pointer
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