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Ion Pumps, Ion Pathways, Ion Sites

  • George Sachs
  • John Cuppoletti
  • Robert D. Gunther
  • Jonathan Kaunitz
  • John Mendlein
  • Edwin C. Rabon
  • Bjorn Wallmark
Part of the New Horizons in Therapeutics book series (NHTH)

Abstract

There has been a rapidly growing list of ATP-fueled ion pumps. Most of these are H+-transporting ATPases ranging from the mitochondrial F1F0 ATPase through the H+ pump of intracellular organelles to the gastric H+-K+ ATPase (Racker, 1976; Cidon and Nelson, 1983; Sachs et al, 1976). In addition to the Ca2+ ATPase of sarcoplasmic reticulum and plasma membrane (Schatzman, 1982), the role of the Ca2+ pump of rough endoplasmic reticulum in fueling a facultative Ca2+ store has been recognized (Berridge, 1984), and its properties are currently of interest.

Keywords

ATPase Activity Acid Secretion Gastric Acid Secretion Proton Transport Renal Medulla 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • George Sachs
    • 1
  • John Cuppoletti
    • 1
  • Robert D. Gunther
    • 1
  • Jonathan Kaunitz
    • 1
  • John Mendlein
    • 1
  • Edwin C. Rabon
    • 2
  • Bjorn Wallmark
    • 3
  1. 1.Wadsworth DivisionCURE, Veterans AdministrationLos AngelesUSA
  2. 2.Department of MedicineUCLA School of MedicineLos AngelesUSA
  3. 3.AB HassleMolndalSweden

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