Growth Cone Guidance and Cell Recognition in Insect Embryos

  • Corey S. Goodman
  • Michael J. Bastiani
  • Chris Q. Doe
  • Sascha Dulac
Part of the Developmental Biology book series (DEBO, volume 3)


In contrast to the complex central nervous system of most vertebrates, the insect CNS is relatively simple. The grasshopper CNS, for example, consists of a brain and a chain of segmental ganglia, each of which contains about 1000 neurons. Most of these neurons can be individually identified according to their unique axonal and dendritic morphology and their unique pattern of synaptic connections. This notion of unique identified neurons first arose dur ing the nineteenth century with descriptions of giant axons, which were repeatedly located in particular regions of the nerve cord. With the advent of intracellular dye-injection techniques (e.g., Stretton and Kravitz, 1968; Pitman et al., 1972; Stewart, 1978), many neurons became individually identified according to the location of their axons and dendrites in the neuropil and connectives. The spatial relationship of these processes to one another within the neuropil was then explored (e.g.,Tyrer and Gregory, 1982); it was shown that the axons and dendrites of identified neurons run in particular regions of specific tracts and commissures.


Growth Cone Drosophila Embryo Neuronal Growth Cone Selective Affinity Neuronal Surface 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Corey S. Goodman
    • 1
  • Michael J. Bastiani
    • 1
  • Chris Q. Doe
    • 1
  • Sascha Dulac
    • 1
  1. 1.Department of Biological SciencesStanford UniversityStanfordUSA

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